SpaceCamp is a 1986 space adventure film inspired by the educational Space Camp held annually on the grounds of the U.S. Space & Rocket Center museum at NASA's Marshall Space Flight Center in Huntsville, Alabama.

Maple Hill Cemetery was established in 1818 on 2 acres of land purchased by the city for $200.00 from Leroy Pope. It is now the oldest and largest cemetery in the state of Alabama, covering almost 100 acres. There are between 80,000 and 100,000 people buried at Maple hill, including five governors of Alabama, five United States senators, and the "Father of Huntsville" Leroy Pope himself.

According to the 2005 publication "Tales of Huntsville Caves", an estimated 240 caves are known, named and catalogued by the Alabama Cave Survey within the city limits and Redstone Arsenal.

The Huntsville Times has been Huntsville's only daily newspaper since 1996, when the Huntsville News closed.

The Keller was an automobile produced by the Keller Motors Corporation of Huntsville between 1947 and 1950. A great deal of the franchise money was spent on development, and only eighteen Kellers were produced before the death of George D. Keller brought an end to production.

On the morning of April 11, 1862, Union troops led by General Ormsby M. Mitchel seized Huntsville in order to sever the Confederacy's rail communications and gain control of the Memphis & Charleston Railroad, striking a major blow to the Confederacy.

A dairy cow called Lily Flagg broke the world record for butter production in 1892. Her Huntsville-resident owner, General Samuel H. Moore, painted his house butter yellow to celebrate.

Both John Hunt and LeRoy Pope were Freemasons and charter members of Helion Lodge #1, the oldest Lodge in Alabama.

Ibi Zoboi's My Life as an Ice Cream Sandwich tells the story of twelve-year-old Ebony-Grace Norfleet, who has lived with her beloved grandfather Jeremiah in Huntsville, Alabama ever since she was little. As one of the first black engineers to integrate NASA, Jeremiah has nurtured Ebony-Grace's love for all things outer space and science fiction--especially Star Wars and Star Trek--but in the summer of 1984, when trouble arises with Jeremiah, Ebony is forced to find her place in a world that's changing at warp speed.

Visitors to the U.S. Space & Rocket Center in Huntsville can see a full-scale replica of the Saturn V rocket, a retired American super heavy-lift launch vehicle developed by NASA under the Apollo program for human exploration of the Moon. The rocket was human-rated, had three stages, and was powered with liquid fuel. It was flown from 1967 to 1973 and used for nine crewed flights to the Moon, and to launch Skylab, the first American space station.